Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 6/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.33 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23635061 | 1.00 | CRBN (0.34) | CRBNPDE3BPDE3ASRCNUAK1 | |
| SCHEMBL23634834 | 1.00 | CRBN (0.34) | CRBNPDE3BPDE3ASRCNUAK1 | |
| SCHEMBL23635055 | 0.91 | CRBN (0.36) | CRBNPDE3BPDE3ANUAK1HRH3 | |
| SCHEMBL23635004 | 0.91 | CRBN (0.36) | CRBNPDE3BPDE3ANUAK1HRH3 | |
| SCHEMBL23635002 | 0.91 | CRBN (0.36) | CRBNPDE3BPDE3ANUAK1HRH3 | |
| SCHEMBL25864756 | 0.89 | CRBN (0.36) | CRBNPDE3BPDE3ANUAK1HRH3 | |
| SCHEMBL23634902 | 0.89 | PDE3B (0.41) | CRBNPDE3BPDE3A | |
| SCHEMBL23634864 | 0.89 | PDE3B (0.41) | CRBNPDE3BPDE3A | |
| SCHEMBL23634843 | 0.89 | PDE3B (0.41) | CRBNPDE3BPDE3A | |
| SCHEMBL23634839 | 0.88 | CRBN (0.37) | CRBNPDE3BPDE3ANUAK1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848363-B1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | MEDSHINE DISCOVERY INC (CN) | 2023-07-19 | — | — | EP | disclosed |
| EP-3848363-A1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | Medshine Discovery Inc. (CN) | 2021-07-14 | — | — | EP | disclosed |