Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 11/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23634955 | 0.89 | CRBN (0.40) | CRBNDDB1POLBKMT2AALDH2 | |
| SCHEMBL23635010 | 0.89 | CRBN (0.49) | CRBNDDB1POLBCYP1A2 | |
| SCHEMBL23635012 | 0.89 | CRBN (0.49) | CRBNDDB1POLBCYP1A2 | |
| SCHEMBL23634960 | 0.89 | CRBN (0.49) | CRBNDDB1POLBCYP1A2 | |
| SCHEMBL23634931 | 0.89 | CRBN (0.41) | CRBNDDB1POLBKMT2AGAA | |
| SCHEMBL23634808 | 0.89 | NUAK1 (0.42) | CRBNDDB1POLBGAA | |
| SCHEMBL23634853 | 0.89 | NUAK1 (0.42) | CRBNDDB1POLBGAA | |
| SCHEMBL23634844 | 0.89 | NUAK1 (0.42) | CRBNDDB1POLBGAA | |
| SCHEMBL24950170 | 0.89 | CRBN (0.38) | CRBNHTTDDB1POLBCA12 | |
| SCHEMBL23635011 | 0.88 | CRBN (0.42) | CRBNDDB1POLBKMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848363-A1 | TRICYCLIC SUBSTITUTED PIPERIDINE DIONE COMPOUND | Medshine Discovery Inc. (CN) | 2021-07-14 | — | — | EP | disclosed |