Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | GPR6 | P46095 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | PLK4 | O00444 | 5/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CCNH | P51946 | 1/20 | 0.33 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18979412 | 0.80 | FFAR4 (0.43) | FFAR4NR4A2DHODHGPR6KCNH2 | |
| SCHEMBL17027768 | 0.68 | FFAR4 (0.47) | FFAR4KCNH2 | |
| SCHEMBL17027851 | 0.65 | PIK3CG (0.49) | FFAR4KCNH2CTPS1 | |
| SCHEMBL22643399 | 0.65 | FFAR4 (0.48) | FFAR4KCNH2CTSKCTSC | |
| SCHEMBL31672280 | 0.64 | CCR6 (0.44) | KCNH2CTPS1 | |
| SCHEMBL18979467 | 0.64 | CCR6 (0.44) | KCNH2CTPS1 | |
| SCHEMBL15624597 | 0.63 | FFAR4 (0.47) | FFAR4KCNH2PLK4CTSKCTSC | |
| SCHEMBL18979399 | 0.63 | DHODH (0.44) | NR4A2DHODHABL1 | |
| SCHEMBL19155112 | 0.61 | CTSC (0.49) | FFAR4KCNH2CTSKCTSC | |
| SCHEMBL18979444 | 0.61 | DHODH (0.51) | FFAR4NR4A2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107909-B1 | ANTIMITOTIC AMIDES FOR THE TREATMENT OF CANCER AND PROLIFERATIVE DISORDERS | FROST BIOLOGIC INC (US) | 2021-07-14 | — | — | EP | disclosed |