SCHEMBL23636152

SCHEMBL23636152

Cc1cccc(-c2cc(-c3ccccc3)nc(-c3ccccc3)n2)n1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.57
CCR8 P51685 1/20 0.57
MEN1 O00255 11/20 0.53
KMT2A Q03164 11/20 0.53
MAPT P10636 7/20 0.53
ALDH1A1 P00352 7/20 0.53
HPGD P15428 7/20 0.53
NTSR1 P30989 1/20 0.53
KDM4E B2RXH2 4/20 0.50
LMNA P02545 3/20 0.50
ADORA2A P29274 2/20 0.50
ADORA1 P30542 2/20 0.50
GLA P06280 1/20 0.50
L3MBTL1 Q9Y468 3/20 0.47
RAB9A P51151 1/20 0.47
TGFBR1 P36897 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
CYP2C19 P33261 1/20 0.46
TDP1 Q9NUW8 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19543724 0.90 MEN1 (0.50) CCR1CCR8MEN1KMT2AMAPT
SCHEMBL23636144 0.89 CCR1 (0.56) CCR1CCR8MEN1KMT2AMAPT
SCHEMBL16189026 0.85 MEN1 (0.56) CCR1CCR8MEN1KMT2AMAPT
SCHEMBL16189386 0.85 MEN1 (0.49) CCR1CCR8MEN1KMT2AMAPT
SCHEMBL16189330 0.84 MEN1 (0.54) CCR1CCR8MEN1KMT2AMAPT
SCHEMBL16189443 0.84 MEN1 (0.54) CCR1CCR8MEN1KMT2AMAPT
SCHEMBL17932287 0.84 MEN1 (0.54) CCR1CCR8MEN1KMT2AMAPT
SCHEMBL23636156 0.83 CCR1 (0.58) CCR1CCR8MEN1KMT2AMAPT
SCHEMBL19009574 0.83 MEN1 (0.47) CCR1CCR8MEN1KMT2AMAPT
SCHEMBL647992 0.82 MEN1 (0.68) CCR1CCR8MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3356369-B1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING TRIAZINE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2022-05-04 EP disclosed
EP-3356368-B1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLYL GROUPS, CARBAZOLYL GROUPS, BENZOFURANE GROUPS OR BENZOTHIOPHENE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2021-07-21 EP disclosed
EP-3150604-B1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLYLYL GROUPS, CARBAZOLYL GROUPS, BENZOFURANE GROUPS OR BENZOTHIOPHENE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2021-07-14 EP disclosed