SCHEMBL23637103

SCHEMBL23637103

CCCn1c(NC(=O)c2cc(C)nn2CC)nc2cc(C(N)=O)cc(OCCCN3CCC(O)CC3)c21

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21789722 0.91 STING1 (0.70) STING1
SCHEMBL21789961 0.91 STING1 (0.86) STING1
SCHEMBL22150299 0.90 STING1 (0.92) STING1
SCHEMBL22857814 0.89 STING1 (0.90) STING1
SCHEMBL19449077 0.87 STING1 (1.00) STING1
SCHEMBL21789757 0.87 STING1 (0.88) STING1
SCHEMBL21789787 0.87 STING1 (0.88) STING1
SCHEMBL28606510 0.87 STING1 (0.80) STING1
SCHEMBL19451510 0.87 STING1 (0.80) STING1
SCHEMBL19437722 0.86 STING1 (0.86) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848366-A1 HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND Adlai Nortye Biopharma Co., Ltd. (CN) 2021-07-14 EP disclosed