SCHEMBL23637210

SCHEMBL23637210

CCn1nc(C)cc1C(=O)Nc1nc2cc(C(N)=O)cc3c2n1[C@@H](CCCn1c(NC(O)c2cc(C)nn2CC)nc2cc(C(N)=O)cc(OCCCNS(=O)(=O)CCN)c21)CO3

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21789630 0.94 STING1 (0.57) STING1
SCHEMBL21790434 0.92 STING1 (0.54) STING1
SCHEMBL23637071 0.90 STING1 (0.54) STING1
SCHEMBL21790423 0.90 STING1 (0.55) STING1
SCHEMBL21776716 0.88 STING1 (0.59) STING1
SCHEMBL23637214 0.87 STING1 (0.51) STING1
SCHEMBL21776846 0.86 STING1 (0.66) STING1
SCHEMBL23637242 0.86 STING1 (0.51) STING1
SCHEMBL21789707 0.85 STING1 (0.61) STING1
SCHEMBL21789947 0.85 STING1 (0.62) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848366-A1 HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND Adlai Nortye Biopharma Co., Ltd. (CN) 2021-07-14 EP disclosed