SCHEMBL23637219

SCHEMBL23637219

CCCn1c(NC(=O)c2cc(C)nn2CC)nc2cc(C(N)=O)cc(OCCCN(C)C(=O)CN3CCN(C)CC3)c21

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23637184 0.95 STING1 (0.72) STING1
SCHEMBL23637062 0.95 STING1 (0.72) STING1
SCHEMBL21790367 0.93 STING1 (0.78) STING1
SCHEMBL21790366 0.90 STING1 (0.77) STING1
SCHEMBL21789954 0.89 STING1 (0.80) STING1
SCHEMBL23637207 0.89 STING1 (0.70) STING1
SCHEMBL21790419 0.89 STING1 (0.73) STING1
SCHEMBL21790049 0.88 STING1 (0.84) STING1
SCHEMBL21790433 0.88 STING1 (0.56) STING1
SCHEMBL22150299 0.86 STING1 (0.92) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848366-A1 HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND Adlai Nortye Biopharma Co., Ltd. (CN) 2021-07-14 EP disclosed