SCHEMBL23637774

SCHEMBL23637774

C[S+]([O-])Cc1nc2c(N)nc3cc(F)ccc3c2n1CC(C)(C)O

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.55
TLR8 Q9NR97 11/20 0.55
NUDT1 P36639 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23637769 0.90 TLR7 (0.57) TLR7TLR8NUDT1
SCHEMBL23637748 0.85 TLR7 (0.69) TLR7TLR8NUDT1
SCHEMBL25927855 0.84 TLR7 (0.63) TLR7TLR8NUDT1
SCHEMBL23637765 0.84 TLR7 (0.56) TLR7TLR8NUDT1
SCHEMBL29639775 0.83 TLR7 (0.78) TLR7TLR8NUDT1
SCHEMBL23637749 0.83 TLR7 (0.56) TLR7TLR8NUDT1
SCHEMBL23304163 0.83 TLR7 (0.78) TLR7TLR8NUDT1
SCHEMBL23637743 0.82 TLR7 (0.61) TLR7TLR8NUDT1
SCHEMBL23637763 0.82 TLR7 (0.60) TLR7TLR8NUDT1
SCHEMBL25927911 0.82 TLR7 (0.79) TLR7TLR8NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4306523-A2 IMIDAZOQUINOLINE COMPOUNDS AND USES THEREOF Birdie Biopharmaceuticals, Inc. (KY) 2024-01-17 EP disclosed
US-20230310469-A1 METHODS OF TREATING SYMPTOMS OF CORONAVIRUS INFECTION WITH TOLL-LIKE-RECEPTOR AGONISTS Accencio LLC 2023-10-05 US disclosed
US-20230310469-A1 METHODS OF TREATING SYMPTOMS OF CORONAVIRUS INFECTION WITH TOLL-LIKE-RECEPTOR AGONISTS Accencio LLC 2023-10-05 US disclosed
EP-3846807-B1 IMIDAZOQUINOLINE COMPOUNDS AND USES THEREOF BIRDIE BIOPHARMACEUTICALS INC (KY) 2023-08-02 EP disclosed
US-20210214354-A1 IMIDAZOQUINOLINE COMPOUNDS AND USES THEREOF BIRDIE BIOPHARMACEUTICALS, INC. (KY) 2021-07-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210214354-A1 IMIDAZOQUINOLINE COMPOUNDS AND USES THEREOF TLR7, TLR8, TLR3 TLR7 1/4885TLR8 2/4885NUDT1 515/4885
US-20230310469-A1 METHODS OF TREATING SYMPTOMS OF CORONAVIRUS INFECTION WITH TOLL-LIKE-RECEPTOR AGONISTS TLR3, TLR7, TLR8 TLR7 2/4885TLR8 3/4885NUDT1 2544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.