Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23637980 | 0.90 | TYK2 (0.72) | TYK2 | |
| SCHEMBL23637846 | 0.88 | TYK2 (0.70) | TYK2 | |
| SCHEMBL23637848 | 0.86 | TYK2 (0.68) | TYK2 | |
| SCHEMBL20073497 | 0.83 | TYK2 (0.81) | TYK2 | |
| SCHEMBL23637971 | 0.80 | TYK2 (0.70) | TYK2 | |
| SCHEMBL20073469 | 0.80 | TYK2 (0.85) | TYK2 | |
| SCHEMBL29883488 | 0.80 | TYK2 (1.00) | TYK2 | |
| SCHEMBL20073225 | 0.80 | TYK2 (1.00) | TYK2 | |
| SCHEMBL23637967 | 0.78 | TYK2 (0.67) | TYK2 | |
| SCHEMBL23637919 | 0.78 | TYK2 (0.72) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3848370-A2 | TYK2 INHIBITORS AND USES THEREOF | Nimbus Lakshmi, Inc. (US) | 2021-07-14 | — | — | EP | disclosed |