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SCHEMBL23638835

SCHEMBL23638835

C=Cc1ccc(C2(c3ccccc3)c3ccccc3-c3ccc(N(c4ccc(-c5ccccc5)cc4)c4ccc(-c5ccc(N(c6ccc(-c7ccccc7)cc6)c6ccc7c(c6)C(c6ccccc6)(c6ccc(C=C)cc6)c6ccccc6-7)cc5F)c(F)c4)cc32)cc1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 2/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ OPRK1 P41145 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23638833 0.98 PDK2 (0.32) PDK2MEN1KMT2AKDM4ELMNA
SCHEMBL23638832 0.95 MEN1 (0.35) PDK2MEN1KMT2AKDM4ELMNA
SCHEMBL21894962 0.94 MEN1 (0.36) PDK2MEN1KMT2AKDM4ELMNA
SCHEMBL21217299 0.94 MEN1 (0.36) PDK2MEN1KMT2AKDM4ELMNA
SCHEMBL23638666 0.94 PDK2 (0.35) PDK2MEN1KMT2AKDM4ELMNA
SCHEMBL21895240 0.94 PDK2 (0.36) PDK2MEN1KMT2AKDM4ELMNA
SCHEMBL21895082 0.93 MEN1 (0.35) PDK2MEN1KMT2AKDM4ELMNA
SCHEMBL21217289 0.92 MEN1 (0.36) PDK2MEN1KMT2AKDM4ELMNA
SCHEMBL21894961 0.92 MEN1 (0.36) PDK2MEN1KMT2AKDM4ELMNA
SCHEMBL23638667 0.92 PDK2 (0.34) PDK2LMNAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021141382-A1 FLUORENE-BASED COMPOUND, ORGANIC LIGHT-EMITTING DEVICE USING SAME, AND MANUFACTURING METHOD THEREFOR 주식회사 엘지화학 2021-07-15 — — WO disclosed