Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29637052 | 0.76 | CYP3A4 (0.36) | PIM1PIM2 | |
| SCHEMBL21068733 | 0.76 | CYP3A4 (0.36) | PIM1PIM2 | |
| SCHEMBL21068734 | 0.76 | CYP3A4 (0.36) | PIM1PIM2 | |
| SCHEMBL23639190 | 0.73 | — | — | |
| SCHEMBL29637086 | 0.73 | CYP3A4 (0.32) | PIM1PIM2 | |
| SCHEMBL21068978 | 0.73 | MAPT (0.39) | — | |
| SCHEMBL21068979 | 0.73 | MAPT (0.39) | — | |
| SCHEMBL21108308 | 0.73 | AAK1 (0.34) | — | |
| SCHEMBL21069104 | 0.65 | CYP3A4 (0.38) | PIM1PIM2 | |
| SCHEMBL21069105 | 0.65 | CYP3A4 (0.38) | PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3475279-B1 | TRIAZOLOPYRIDINES AS GAMMA-SECRETASE MODULATORS | HOFFMANN LA ROCHE (CH) | 2021-07-14 | — | — | EP | disclosed |