Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TLR2 | O60603 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11134722 | 0.89 | CYP3A4 (0.60) | CYP3A4PLA2G2CMMP9MMP8MMP14 | |
| SCHEMBL23640099 | 0.87 | SOAT1 (0.42) | CYP3A4PLA2G2CCYP1A2CYP2C19SOAT1 | |
| SCHEMBL27000266 | 0.81 | PLA2G2C (0.44) | CYP3A4PLA2G2CMMP9MMP8MMP14 | |
| SCHEMBL5472138 | 0.80 | CYP3A4 (0.55) | CYP3A4PLA2G2CMMP9MMP8MMP14 | |
| SCHEMBL29044598 | 0.79 | PLA2G2C (0.56) | PLA2G2CMEN1KMT2ATSHRTDP1 | |
| SCHEMBL5472374 | 0.79 | CYP3A4 (0.58) | CYP3A4PLA2G2CMMP9MMP8MMP14 | |
| SCHEMBL5478153 | 0.79 | CYP3A4 (0.58) | CYP3A4PLA2G2CMMP9MMP8MMP14 | |
| SCHEMBL21207649 | 0.79 | SOAT1 (0.53) | CYP3A4CYP1A2CYP2C19SOAT1MEN1 | |
| SCHEMBL5476832 | 0.79 | CYP3A4 (0.58) | CYP3A4PLA2G2CMMP9MMP8MMP14 | |
| SCHEMBL11080985 | 0.79 | SOAT1 (0.53) | CYP3A4CYP1A2CYP2C19SOAT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210214316-A1 | ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS | SAGARD HOLDINGS MANAGER LP, AS ADMINISTRATIVE AGENT (CA) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214316-A1 | ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS | NCOA1, NCOR1, NCOA3 | CYP3A4 3382/4885PLA2G2C 3099/4885MMP9 3584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.