Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.42 |
| ▸ | MC4R | P32245 | 13/20 | 0.41 |
| ▸ | MC5R | P33032 | 13/20 | 0.41 |
| ▸ | MC3R | P41968 | 10/20 | 0.41 |
| ▸ | MC1R | Q01726 | 10/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15016822 | 0.88 | MC4R (0.44) | MC4RMC5RMC3RMC1R | |
| SCHEMBL1309343 | 0.88 | MC4R (0.44) | MC4RMC5RMC3RMC1R | |
| SCHEMBL1324259 | 0.88 | MC4R (0.41) | MC4RMC5RMC3RMC1RKMT2A | |
| SCHEMBL1311389 | 0.87 | MC4R (0.43) | MC4RMC5RMC3RMC1RKMT2A | |
| Trifluoroacetic Acid SCHEMBL1308833 | 0.85 | MC4R (0.44) | MC4RMC5RMC3RMC1R | |
| SCHEMBL2320057 | 0.84 | MC4R (0.41) | MC4RMC5RMC3RMC1RHTT | |
| SCHEMBL15272893 | 0.84 | MC4R (0.44) | MC4RMC5RMC3RMC1RKMT2A | |
| SCHEMBL1309703 | 0.84 | MC4R (0.44) | MC4RMC5RMC3RMC1RKMT2A | |
| SCHEMBL1308356 | 0.84 | MC1R (0.56) | RENMC4RMC5RMC3RMC1R | |
| SCHEMBL1308793 | 0.84 | MC4R (0.42) | MC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012131090-A1 | METHOD FOR TREATMENT OF XERODERMA PIGMENTOSUM | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2012-10-04 | — | — | WO | disclosed |
| EP-2352729-A1 | MELANOCORTIN RECEPTOR ANTAGONIST COMPOUNDS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | Galderma Research & Development (FR) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010052256-A1 | MELANOCORTIN RECEPTOR ANTAGONIST COMPOUNDS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-05-14 | — | — | WO | disclosed |