Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 3/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.31 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3616377 | 1.00 | ANPEP (0.34) | ANPEPENPEPGPR88PSEN1PSEN2 | |
| SCHEMBL3616374 | 1.00 | ANPEP (0.34) | ANPEPENPEPGPR88PSEN1PSEN2 | |
| SCHEMBL2364187 | 1.00 | ANPEP (0.34) | ANPEPENPEPGPR88PSEN1PSEN2 | |
| SCHEMBL2364257 | 1.00 | ANPEP (0.34) | ANPEPENPEPGPR88PSEN1PSEN2 | |
| SCHEMBL2364260 | 1.00 | ANPEP (0.34) | ANPEPENPEPGPR88PSEN1PSEN2 | |
| SCHEMBL3616372 | 1.00 | ANPEP (0.34) | ANPEPENPEPGPR88PSEN1PSEN2 | |
| SCHEMBL3642072 | 0.96 | ANPEP (0.33) | ANPEPENPEPGPR88 | |
| SCHEMBL3336027 | 0.96 | ANPEP (0.33) | ANPEPENPEPGPR88 | |
| SCHEMBL3336032 | 0.96 | ANPEP (0.33) | ANPEPENPEPGPR88 | |
| SCHEMBL3600815 | 0.92 | ANPEP (0.33) | ANPEPENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081927-B1 | PIPERIDINE DERIVATIVES AS RENIN INHIBITORS | VITAE PHARMACEUTICALS INC (US) | 2011-08-17 | — | — | EP | claimed |