Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15581120 | 0.82 | KCNJ1 (0.44) | KCNJ1L3MBTL1KDM4EHPGDMAPT | |
| SCHEMBL29956704 | 0.82 | KCNJ1 (0.44) | KCNJ1L3MBTL1KDM4EHPGDMAPT | |
| SCHEMBL31003291 | 0.81 | KCNJ1 (0.42) | KCNJ1L3MBTL1KDM4EHPGDMAPT | |
| SCHEMBL932013 | 0.81 | KCNJ1 (0.42) | KCNJ1L3MBTL1KDM4EHPGDMAPT | |
| SCHEMBL29123392 | 0.73 | P4HTM (0.64) | KCNJ1L3MBTL1HPGDMAPTRAB9A | |
| SCHEMBL30626041 | 0.73 | P4HTM (0.64) | KCNJ1L3MBTL1HPGDMAPTRAB9A | |
| SCHEMBL1092282 | 0.71 | KCNJ1 (0.47) | KCNJ1L3MBTL1HPGDMAPTRAB9A | |
| SCHEMBL31290288 | 0.71 | HDAC1 (0.62) | KCNJ1L3MBTL1KDM4EHPGDMAPT | |
| SCHEMBL3595340 | 0.71 | KCNJ1 (0.47) | KCNJ1L3MBTL1HPGDMAPTRAB9A | |
| SCHEMBL30269694 | 0.71 | P4HTM (0.54) | KCNJ1L3MBTL1KDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210215670-A1 | COMPOUNDS AND METHODS OF IDENTIFYING, SYNTHESIZING, OPTIMIZING AND PROFILING PROTEIN MODULATORS | HMI Medical Innovations, LLC | 2021-07-15 | — | — | US | disclosed |