SCHEMBL23643177

SCHEMBL23643177

c1ccc(-c2nc(-c3ccc(-c4ccc(-c5ccc(-c6cccnc6)cc5)cc4)cc3)nc(-c3cccc4c3-c3ccccc3C43c4ccccc4Oc4ccccc43)n2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 5/20 0.42
SMN1; SMN2 Q16637 3/20 0.38
ALDH1A1 P00352 3/20 0.38
MAPT P10636 3/20 0.38
TP53 P04637 2/20 0.38
KDM4E B2RXH2 2/20 0.38
HPGD P15428 2/20 0.38
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
HSD17B10 Q99714 1/20 0.38
POLB P06746 1/20 0.37
TSHR P16473 1/20 0.37
MKNK1 Q9BUB5 1/20 0.36
MKNK2 Q9HBH9 1/20 0.36
BACE1 P56817 2/20 0.35
KCNH2 Q12809 1/20 0.35
USP1 O94782 5/20 0.34
WDR48 Q8TAF3 5/20 0.34
CYP19A1 P11511 2/20 0.34
CYP2A6 P11509 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21151135 0.94 PDK2 (0.41) PDK2SMN1; SMN2ALDH1A1MAPTTP53
SCHEMBL24648475 0.94 PDK2 (0.40) PDK2SMN1; SMN2ALDH1A1MAPTTP53
SCHEMBL22037568 0.91 PDK2 (0.47) PDK2SMN1; SMN2ALDH1A1MAPTTP53
SCHEMBL22037905 0.91 PDK2 (0.47) PDK2SMN1; SMN2ALDH1A1MAPTTP53
SCHEMBL21651298 0.91 TSHR (0.35) PDK2SMN1; SMN2ALDH1A1MAPTTP53
SCHEMBL21151227 0.91 TSHR (0.35) PDK2SMN1; SMN2ALDH1A1MAPTTP53
SCHEMBL21394573 0.91 TSHR (0.35) PDK2SMN1; SMN2ALDH1A1MAPTTP53
SCHEMBL21151704 0.89 TSHR (0.36) PDK2SMN1; SMN2ALDH1A1MAPTTP53
SCHEMBL24648476 0.88 PDK2 (0.44) PDK2SMN1; SMN2ALDH1A1MAPTTP53
SCHEMBL21658335 0.88 MEN1 (0.33) PDK2ALDH1A1MAPTKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210217967-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-07-15 US disclosed