Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 12/20 | 0.39 |
| ▸ | DRD3 | P35462 | 10/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23645331 | 1.00 | PDE4B (0.41) | PDE4BMALT1PDE4APDE4CDRD2 | |
| SCHEMBL23645327 | 0.91 | MALT1 (0.42) | PDE4BMALT1PDE4APDE4CDRD2 | |
| SCHEMBL23645326 | 0.91 | MALT1 (0.42) | PDE4BMALT1PDE4APDE4CDRD2 | |
| SCHEMBL23645317 | 0.90 | MALT1 (0.40) | PDE4BMALT1PDE4APDE4CDRD2 | |
| SCHEMBL23645316 | 0.90 | MALT1 (0.40) | PDE4BMALT1PDE4APDE4CDRD2 | |
| SCHEMBL23645363 | 0.90 | MALT1 (0.42) | PDE4BMALT1PDE4APDE4CDRD2 | |
| SCHEMBL23645358 | 0.90 | MALT1 (0.42) | PDE4BMALT1PDE4APDE4CDRD2 | |
| SCHEMBL21810902 | 0.89 | MALT1 (0.41) | PDE4BMALT1PDE4APDE4CDRD2 | |
| SCHEMBL23645355 | 0.89 | MALT1 (0.41) | PDE4BMALT1PDE4APDE4CDRD2 | |
| SCHEMBL23645359 | 0.89 | MALT1 (0.41) | PDE4BMALT1PDE4APDE4CDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12421225-B2 | Heteroaromatic amide derivative and medicament containing the same | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2025-09-23 | — | — | US | disclosed |
| EP-3851436-B1 | NOVEL HETEROAROMATIC AMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | KAKEN PHARMA CO LTD (JP) | 2024-06-12 | — | — | EP | disclosed |
| US-20230086366-A1 | Novel heteroaromatic amide derivative and medicament containing the same | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2023-03-23 | — | — | US | disclosed |
| EP-3851436-A1 | NOVEL HETEROAROMATIC AMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2021-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230086366-A1 | Novel heteroaromatic amide derivative and medicament containing the same | SCN7A, HCN4, SCN4A | PDE4B 1065/4885MALT1 2051/4885PDE4A 1135/4885 |
| US-12421225-B2 | Heteroaromatic amide derivative and medicament containing the same | SCN7A, HCN4, SCN4A | PDE4B 967/4885MALT1 2096/4885PDE4A 1027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.