Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.63 |
| ▸ | EGFR | P00533 | 12/20 | 0.60 |
| ▸ | JAK3 | P52333 | 3/20 | 0.51 |
| ▸ | BMX | P51813 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23645440 | 1.00 | BTK (0.63) | BTKEGFRJAK3BMX | |
| SCHEMBL21707226 | 0.85 | BTK (0.83) | BTKEGFR | |
| SCHEMBL29948723 | 0.85 | BTK (0.83) | BTKEGFR | |
| SCHEMBL22442572 | 0.85 | BTK (0.83) | BTKEGFR | |
| SCHEMBL28536320 | 0.85 | BTK (0.83) | BTKEGFR | |
| SCHEMBL29948662 | 0.85 | BTK (0.83) | BTKEGFR | |
| SCHEMBL29948930 | 0.83 | BTK (0.67) | BTKEGFRJAK3BMX | |
| SCHEMBL28551061 | 0.80 | BTK (0.62) | BTKEGFRJAK3BMX | |
| SCHEMBL28551060 | 0.80 | BTK (0.62) | BTKEGFRJAK3BMX | |
| SCHEMBL22496626 | 0.77 | BTK (1.00) | BTKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3851438-A1 | BTK INHIBITOR, PHARMACEUTICALLY ACCEPTABLE SALT, POLYMORPH AND APPLICATION THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2021-07-21 | — | — | EP | disclosed |