SCHEMBL2364550

SCHEMBL2364550

Cc1ccc2c(c1)nc(N)c1ncc(CCc3ccc(OC(C)CCC(=O)O)cc3C)cc12

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2364753 0.92 TLR7 (0.56) TLR7
SCHEMBL1008967 0.89 TLR7 (0.78) TLR7
SCHEMBL1062047 0.87 TLR7 (0.79) TLR7
SCHEMBL2354182 0.87 TLR7 (0.64) TLR7
SCHEMBL1061300 0.87 TLR7 (0.78) TLR7
SCHEMBL1062269 0.86 TLR7 (0.76) TLR7
SCHEMBL1058676 0.86 TLR7 (0.79) TLR7
SCHEMBL2364546 0.85 TLR7 (0.72) TLR7
SCHEMBL16735805 0.85 TLR7 (0.70) TLR7
SCHEMBL1062584 0.84 TLR7 (0.70) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2512478-A1 HOMOGENEOUS SUSPENSION OF IMMUNOPOTENTIATING COMPOUNDS AND USES THEREOF Novartis AG (CH) 2012-10-24 EP disclosed
WO-2011084549-A1 HOMOGENEOUS SUSPENSION OF IMMUNOPOTENTIATING COMPOUNDS AND USES THEREOF NOVARTIS AG (CH) 2011-07-14 WO disclosed