Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 8/20 | 0.79 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254380 | 1.00 | PDPK1 (0.79) | PDPK1KEAP1TDP1NPC1CASP3 | |
| SCHEMBL2577872 | 1.00 | PDPK1 (0.79) | PDPK1KEAP1TDP1NPC1CASP3 | |
| SCHEMBL657640 | 0.90 | PDPK1 (0.75) | PDPK1FFAR1HDAC2GPR52HDAC1 | |
| SCHEMBL658241 | 0.90 | PDPK1 (0.75) | PDPK1FFAR1HDAC2GPR52HDAC1 | |
| SCHEMBL657639 | 0.90 | PDPK1 (0.75) | PDPK1FFAR1HDAC2GPR52HDAC1 | |
| SCHEMBL655773 | 0.89 | PDPK1 (0.73) | PDPK1KEAP1TDP1NPC1CASP3 | |
| SCHEMBL10252862 | 0.89 | PDPK1 (0.73) | PDPK1TDP1NPC1RAB9AALDH1A1 | |
| SCHEMBL657111 | 0.89 | PDPK1 (1.00) | PDPK1KEAP1FFAR1GPR52KMT2A | |
| SCHEMBL657791 | 0.89 | PDPK1 (1.00) | PDPK1FFAR1KMT2AHTT | |
| SCHEMBL656662 | 0.89 | PDPK1 (0.73) | PDPK1NPC1RAB9AALDH1A1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349999-B1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIV SAARLAND (DE) | 2016-01-27 | — | — | EP | claimed |
| US-11932870-B2 | Compositions and methods for immune cell modulation in adoptive immunotherapies | FATE THERAPEUTICS, INC. | 2024-03-19 | — | — | US | disclosed |
| CN-116376826-A | Compositions and methods for immune cell modulation in adoptive immunotherapy | 菲特治疗公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-108473959-B | Compositions and methods for immune cell modulation in adoptive immunotherapy | 菲特治疗公司 | 2023-04-21 | — | — | CN | disclosed |
| US-20220401487-A1 | COMPOSITIONS AND METHODS FOR IMMUNE CELL MODULATION IN ADOPTIVE IMMUNOTHERAPIES | FATE THERAPEUTICS, INC. | 2022-12-22 | — | — | US | disclosed |
| US-11413309-B2 | Compositions and methods for immune cell modulation in adoptive immunotherapies | FATE THERAPEUTICS, INC. (US) | 2022-08-16 | — | — | US | disclosed |
| EP-3936608-A1 | REPROGRAMMING CELLS | The Scripps Research Institute (US) | 2022-01-12 | — | — | EP | disclosed |
| US-20210393695-A1 | COMPOSITIONS AND METHODS FOR IMMUNE CELL MODULATION IN ADOPTIVE IMMUNOTHERAPIES | FATE THERAPEUTICS, INC. | 2021-12-23 | — | — | US | disclosed |
| EP-3199623-B1 | REPROGRAMMING CELLS | SCRIPPS RESEARCH INST (US) | 2021-07-28 | — | — | EP | disclosed |
| US-20210095257-A1 | REPROGRAMMING CELLS | THE SCRIPPS RESEARCH INSTITUTE | 2021-04-01 | — | — | US | disclosed |
| WO-2017127729-A1 | COMPOSITIONS AND METHODS FOR IMMUNE CELL MODULATION IN ADOPTIVE IMMUNOTHERAPIES | FATE THERAPEUTICS, INC. (US) | 2017-07-27 | — | — | WO | disclosed |
| WO-2017127755-A1 | COMPOSITIONS AND METHODS FOR IMMUNE CELL MODULATION IN ADOPTIVE IMMUNOTHERAPIES | FATE THERAPEUTICS, INC. (US) | 2017-07-27 | — | — | WO | disclosed |
| US-9657274-B2 | Reprogramming cells | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-05-23 | — | — | US | disclosed |
| EP-2553086-B1 | REPROGRAMMING CELLS | SCRIPPS RESEARCH INST (US) | 2017-04-19 | — | — | EP | disclosed |
| US-20160257938-A1 | Reprogramming Cells | THE SCRIPPS RESEARCH INSTITUTE | 2016-09-08 | — | — | US | disclosed |
| US-9315779-B2 | Reprogramming cells | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-04-19 | — | — | US | disclosed |
| US-20130323833-A1 | REPROGRAMMING CELLS | THE SCRIPPS RESEARCH INSTITUTE | 2013-12-05 | — | — | US | disclosed |
| EP-2553086-A1 | REPROGRAMMING CELLS | The Scripps Research Institute (US) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011123572-A1 | REPROGRAMMING CELLS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-10-06 | — | — | WO | disclosed |
| EP-2349999-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | Universität des Saarlandes (DE) | 2011-08-03 | — | — | EP | disclosed |