Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2354169 | 0.91 | TLR7 (0.72) | TLR7 | |
| SCHEMBL2364750 | 0.87 | TLR7 (0.58) | TLR7 | |
| SCHEMBL1060970 | 0.86 | TLR7 (0.63) | TLR7 | |
| SCHEMBL1060866 | 0.86 | TLR7 (0.60) | TLR7 | |
| SCHEMBL1009109 | 0.85 | TLR7 (0.64) | TLR7 | |
| SCHEMBL1008912 | 0.85 | TLR7 (0.63) | TLR7 | |
| SCHEMBL1062693 | 0.84 | TLR7 (0.63) | TLR7 | |
| SCHEMBL1062272 | 0.84 | TLR7 (0.61) | TLR7 | |
| SCHEMBL1010201 | 0.83 | TLR7 (0.64) | TLR7 | |
| SCHEMBL1062534 | 0.83 | TLR7 (0.59) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268618-B1 | COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS | NOVARTIS AG (CH) | 2015-05-27 | — | — | EP | claimed |
| EP-2512478-A1 | HOMOGENEOUS SUSPENSION OF IMMUNOPOTENTIATING COMPOUNDS AND USES THEREOF | Novartis AG (CH) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011084549-A1 | HOMOGENEOUS SUSPENSION OF IMMUNOPOTENTIATING COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2011-07-14 | — | — | WO | disclosed |