SCHEMBL236516

SCHEMBL236516

CC(C)CN(CC#N)CC(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 1.00
MAPK1 P28482 1/20 1.00
DPP4 P27487 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20000110 0.94 CYP1A2 (0.90) CYP1A2MAPK1DPP4CA12CA1
SCHEMBL24693741 0.85 CYP1A2 (0.74) CYP1A2MAPK1DPP4
SCHEMBL20756109 0.85 CYP1A2 (0.74) CYP1A2MAPK1
SCHEMBL20755993 0.79 CYP1A2 (0.65) CYP1A2MAPK1DPP4
SCHEMBL11702536 0.74 CYP1A2 (0.58) CYP1A2MAPK1DPP4
SCHEMBL150669 0.74 MAPK1 (0.58) CYP1A2MAPK1CA12CA1CA2
SCHEMBL12059480 0.74 CYP1A2 (0.58) CYP1A2MAPK1
SCHEMBL23074853 0.73 CYP1A2 (0.55) CYP1A2MAPK1MAOB
SCHEMBL7676701 0.72 CYP1A2 (0.56) CYP1A2MAPK1CA12CA1CA2
SCHEMBL1583185 0.72 CYP1A2 (0.56) CYP1A2MAPK1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4737568-A Curable resin from bis-imide amino acid hydrazide and alkenyl phenol or ether THE BOOTS COMPANY PLC (GB) 1988-04-12 US claimed
EP-0212808-A2 Curable resins Technochemie GmbH - Verfahrenstechnik (DE) 1987-03-04 EP claimed
US-9512333-B2 Phosphoric acid resistant polymaleimide prepolymer compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2016-12-06 US disclosed
EP-2417168-B1 PHOSPHORIC ACID RESISTANT POLYMALEIMIDE PREPOLYMER COMPOSITIONS HUNTSMAN ADV MAT AMERICAS INC (US) 2014-11-26 EP disclosed
EP-2710045-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS Huntsman Advanced Materials Americas LLC (US) 2014-03-26 EP disclosed
US-20140057086-A1 Halogen Free Thermoset Resin System for Low Dielectric Loss at High Frequency Applications HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2014-02-27 US disclosed
US-20130231021-A1 Phosphoric Acid Resistant Polymaleimide Prepolymer Compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2013-09-05 US disclosed
US-8445699-B2 Phosphoric acid resistant polymaleimide prepolymer compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2013-05-21 US disclosed
WO-2012158415-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2012-11-22 WO disclosed
EP-2417168-A1 PHOSPHORIC ACID RESISTANT POLYMALEIMIDE PREPOLYMER COMPOSITIONS Huntsman Advanced Materials Americas LLC (US) 2012-02-15 EP disclosed
US-20120003892-A1 Phosphoric Acid Resistant Polymaleimide Prepolymer Compositions Huntsman Advanced Materials Americans LLC (US) 2012-01-05 US disclosed
EP-0212808-A2 Curable resins Technochemie GmbH - Verfahrenstechnik (DE) 1987-03-04 EP disclosed
EP-0175648-A2 Heat-hardenable compositions containing a polymaleinimide and a bicyclo[2.2.1]heptene-5-2,3-dicarboximide, and their use CIBA-GEIGY AG (CH) 1986-03-26 EP disclosed
US-4131707-A POLYMALEIMIDES CIBA-GEIGY CORPORATION (US) 1978-12-26 US disclosed
US-4100140-A REACTING POLYMALEIMIDES WITH ALKENYLPHENOLS OR ALKENYLPHENOL ETHERS, POLYMERIZATION CATALYSTS CIBA-GEIGY CORPORATION (US) 1978-07-11 US disclosed
US-4076697-A FROM POLYIMIDES AND POLYCARBOXYLIC ACIDS IN THE PRESENCE OF AN AMINE CIBA-GEIGY CORPORATION (US) 1978-02-28 US disclosed
US-4066621-A CURABLE MIXTURES BASED ON POLYIMIDES OF UNSATURATED DICARBOXYLIC ACIDS AND INDOLE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1978-01-03 US disclosed
US-4065433-A Process for the manufacture of polyaddition products containing imide groups CIBA-GEIGY CORPORATION (US) 1977-12-27 US disclosed
US-4046777-A INTERMEDIATES FOR HEAT-RESISTANT POLYMERS CIBA-GEIGY CORPORATION (US) 1977-09-06 US disclosed
US-4038251-A PROCESS FOR THE MANUFACTURE OF POLYADDITION PRODUCTS CONTAINING IMIDE GROUPS BY REACTION OF POLYMALEIMIDES WITH POLYHYDRIC PHENOLS USING AMINE CATALYST CIBA-GEIGY CORPORATION (US) 1977-07-26 US disclosed