Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 20/20 | 0.86 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18041434 | 0.93 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL20492761 | 0.92 | TLR8 (0.83) | TLR8TLR7 | |
| SCHEMBL18041400 | 0.92 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL20442316 | 0.91 | TLR8 (0.82) | TLR8TLR7 | |
| SCHEMBL20840991 | 0.91 | TLR8 (0.84) | TLR8TLR7 | |
| SCHEMBL24164280 | 0.91 | TLR8 (0.84) | TLR8TLR7 | |
| SCHEMBL18041427 | 0.90 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL18041320 | 0.90 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL20841075 | 0.90 | TLR8 (0.84) | TLR8TLR7 | |
| SCHEMBL18041362 | 0.89 | TLR8 (1.00) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3949969-A2 | BENZAZEPINE COMPOUNDS, CONJUGATES, AND USES THEREOF | Silverback Therapeutics, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| EP-3595668-B1 | BENZAZEPINE COMPOUNDS, CONJUGATES, AND USES THEREOF | SILVERBACK THERAPEUTICS INC (US) | 2021-07-21 | — | — | EP | disclosed |