SCHEMBL23652104

SCHEMBL23652104

COc1cc(Cl)cc(/C=N/CCCSO)c1O

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 9/20 0.53
GAA P10253 2/20 0.49
KDM4E B2RXH2 1/20 0.49
ALDH1A1 P00352 1/20 0.49
CA12 O43570 2/20 0.45
PTK6 Q13882 2/20 0.44
PSMD14 O00487 1/20 0.39
DUSP3 P51452 1/20 0.39
PTPN5 P54829 1/20 0.39
PTPN11 Q06124 1/20 0.39
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23652331 0.80 ERN1 (0.51) ERN1GAAKDM4EALDH1A1CA12
SCHEMBL13944216 0.80 ERN1 (0.51) ERN1GAAKDM4EALDH1A1CA12
SCHEMBL2314960 0.73 GAA (0.63) ERN1GAAKDM4EALDH1A1PTK6
SCHEMBL12768067 0.69 ERN1 (1.00) ERN1CA12MAPTKMT2A
SCHEMBL455724 0.68 ERN1 (1.00) ERN1GAAKDM4EALDH1A1MAPT
SCHEMBL30933727 0.68 ERN1 (1.00) ERN1GAAKDM4EALDH1A1MAPT
SCHEMBL29229529 0.67 CA12 (0.39) ERN1GAAKDM4EALDH1A1CA12
SCHEMBL14669050 0.67 ERN1 (0.56) ERN1GAAALDH1A1CA12MAPT
SCHEMBL1541991 0.66 ERN1 (0.64) ERN1GAAKDM4EALDH1A1CA12
SCHEMBL2222204 0.66 CA12 (0.58) ERN1GAAKDM4EALDH1A1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2862581-B1 Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid BHI LP (CA) 2021-08-11 EP disclosed
EP-3851447-A1 METHODS, COMPOUNDS, COMPOSITIONS AND VEHICLES FOR DELIVERING 3-AMINO-1-PROPANESULFONIC ACID BHI Limited Partnership (CA) 2021-07-21 EP disclosed