Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 18/20 | 0.69 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.65 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.55 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23653208 | 0.87 | FGFR4 (0.74) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL21166349 | 0.84 | FGFR4 (0.74) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16134022 | 0.84 | FGFR4 (0.74) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16134030 | 0.83 | FGFR1 (0.77) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16071730 | 0.82 | FGFR4 (1.00) | FGFR4 | |
| SCHEMBL24225231 | 0.82 | FGFR4 (0.97) | FGFR4 | |
| SCHEMBL16071786 | 0.82 | FGFR4 (0.97) | FGFR4 | |
| SCHEMBL16071804 | 0.82 | FGFR4 (0.97) | FGFR4 | |
| SCHEMBL16071492 | 0.82 | FGFR1 (0.82) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16071437 | 0.82 | FGFR4 (1.00) | FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968337-B1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE CAR LLC (BM) | 2021-07-21 | — | — | EP | disclosed |