SCHEMBL23652948

SCHEMBL23652948

C=CC(=O)NC1CCCCC1Nc1ncc2c(n1)N(C)C(=O)N(c1cc(OC)cc(C(F)(F)F)c1)C2

nearest known ligand 0.86

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FGFR4 P22455 20/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24224988 1.00 FGFR4 (0.86) FGFR4
SCHEMBL23652937 1.00 FGFR4 (0.86) FGFR4
SCHEMBL16071613 1.00 FGFR4 (0.86) FGFR4
SCHEMBL16071758 0.93 FGFR4 (1.00) FGFR4
SCHEMBL24690853 0.92 FGFR4 (0.72) FGFR4
SCHEMBL19069193 0.91 FGFR4 (0.70) FGFR4
SCHEMBL16071510 0.88 FGFR4 (1.00) FGFR4
SCHEMBL23653320 0.88 FGFR4 (1.00) FGFR4
SCHEMBL24225015 0.85 FGFR4 (0.62) FGFR4
SCHEMBL24225205 0.85 FGFR4 (1.00) FGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2968337-B1 HETEROARYL COMPOUNDS AND USES THEREOF CELGENE CAR LLC (BM) 2021-07-21 — — EP disclosed
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