SCHEMBL23653106

SCHEMBL23653106

C=CC(=O)N[C@H]1CCCC[C@H]1Nc1ncc2c(n1)N(C)C(=O)N(c1c(C)c(OC)cc(OC)c1Cl)C2

nearest known ligand 0.91

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FGFR4 P22455 20/20 0.91

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16071965 0.95 FGFR4 (1.00) FGFR4
SCHEMBL16071730 0.95 FGFR4 (1.00) FGFR4
SCHEMBL16071437 0.95 FGFR4 (1.00) FGFR4
SCHEMBL24225112 0.95 FGFR4 (0.84) FGFR4
SCHEMBL16071606 0.95 FGFR4 (0.84) FGFR4
SCHEMBL23653426 0.95 FGFR4 (0.84) FGFR4
SCHEMBL24225231 0.94 FGFR4 (0.97) FGFR4
SCHEMBL16071804 0.94 FGFR4 (0.97) FGFR4
SCHEMBL16071786 0.94 FGFR4 (0.97) FGFR4
SCHEMBL16071868 0.92 FGFR4 (0.90) FGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2968337-B1 HETEROARYL COMPOUNDS AND USES THEREOF CELGENE CAR LLC (BM) 2021-07-21 — — EP disclosed
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