Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.71 |
| ▸ | FGFR4 | P22455 | 17/20 | 0.60 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.54 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.54 |
| ▸ | BMX | P51813 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16071583 | 0.96 | FGFR1 (0.70) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL16071492 | 0.83 | FGFR1 (0.82) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL16134030 | 0.83 | FGFR1 (0.77) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL15413202 | 0.83 | FGFR1 (1.00) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL19363708 | 0.81 | FGFR1 (0.51) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL16134009 | 0.81 | FGFR1 (0.69) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL16071784 | 0.81 | FGFR1 (0.69) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL16071581 | 0.80 | FGFR4 (0.64) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL16134008 | 0.78 | FGFR1 (0.67) | FGFR1FGFR4FGFR2FGFR3 | |
| SCHEMBL23653293 | 0.78 | FGFR4 (0.68) | FGFR1FGFR4FGFR2FGFR3BMX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968337-B1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE CAR LLC (BM) | 2021-07-21 | — | — | EP | disclosed |