Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 3/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 9/20 | 0.48 |
| ▸ | EGFR | P00533 | 6/20 | 0.47 |
| ▸ | FGFR4 | P22455 | 8/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 6/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24225085 | 0.85 | FGFR1 (0.54) | WEE1FGFR1EGFRFGFR4FGFR2 | |
| SCHEMBL24225025 | 0.85 | FGFR1 (0.50) | WEE1FGFR1EGFRFGFR4FGFR2 | |
| SCHEMBL16071792 | 0.80 | FGFR1 (0.57) | WEE1FGFR1EGFRFGFR4FGFR2 | |
| SCHEMBL16072109 | 0.76 | FGFR1 (0.51) | WEE1FGFR1EGFRFGFR4FGFR2 | |
| SCHEMBL16071805 | 0.74 | FGFR1 (0.50) | WEE1FGFR1EGFRFGFR4FGFR2 | |
| SCHEMBL15413205 | 0.73 | FGFR1 (0.68) | WEE1FGFR1EGFRFGFR4FGFR2 | |
| SCHEMBL16071530 | 0.73 | FGFR1 (0.54) | WEE1FGFR1EGFRFGFR4FGFR2 | |
| SCHEMBL16071534 | 0.73 | FGFR1 (0.61) | WEE1FGFR1EGFRFGFR4FGFR2 | |
| SCHEMBL16071791 | 0.71 | FGFR1 (0.59) | WEE1FGFR1EGFRFGFR4FGFR2 | |
| SCHEMBL16071789 | 0.70 | FGFR1 (0.61) | WEE1FGFR1EGFRFGFR4FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968337-B1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE CAR LLC (BM) | 2021-07-21 | — | — | EP | disclosed |