Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 20/20 | 0.72 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.72 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.72 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16133998 | 0.96 | FGFR4 (0.78) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL23653035 | 0.94 | FGFR4 (0.64) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL24225046 | 0.92 | FGFR4 (0.62) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL23653030 | 0.88 | FGFR4 (0.76) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16133979 | 0.85 | FGFR4 (0.92) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16133999 | 0.85 | FGFR4 (0.79) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL23653091 | 0.85 | FGFR4 (0.74) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16071725 | 0.84 | FGFR4 (0.78) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16071428 | 0.84 | FGFR4 (0.82) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16071432 | 0.83 | FGFR4 (0.81) | FGFR4FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3943087-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | Celgene CAR LLC (BM) | 2022-01-26 | — | — | EP | disclosed |
| EP-2968337-B1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE CAR LLC (BM) | 2021-07-21 | — | — | EP | disclosed |