Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 12/20 | 0.54 |
| ▸ | BMX | P51813 | 7/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.51 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23653263 | 0.83 | FGFR1 (0.65) | FGFR4BMXFGFR1 | |
| SCHEMBL23653284 | 0.80 | FGFR4 (0.66) | FGFR4BMXFGFR1FGFR2FGFR3 | |
| SCHEMBL16134030 | 0.79 | FGFR1 (0.77) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL24225244 | 0.76 | FGFR1 (0.55) | FGFR4BMXFGFR1 | |
| SCHEMBL16071493 | 0.74 | FGFR4 (0.81) | FGFR4BMXFGFR1FGFR2FGFR3 | |
| SCHEMBL16133992 | 0.74 | FGFR4 (0.70) | FGFR4BMXFGFR1FGFR2FGFR3 | |
| SCHEMBL16071762 | 0.74 | FGFR4 (0.67) | FGFR4BMXFGFR1FGFR2FGFR3 | |
| SCHEMBL16137292 | 0.72 | FGFR4 (0.71) | FGFR4BMXFGFR1FGFR2FGFR3 | |
| SCHEMBL16137337 | 0.72 | FGFR4 (0.75) | FGFR4BMXFGFR1FGFR2FGFR3 | |
| SCHEMBL16137329 | 0.72 | FGFR4 (0.75) | FGFR4BMXFGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968337-B1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE CAR LLC (BM) | 2021-07-21 | — | — | EP | disclosed |