Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29374255 | 0.93 | BCL2 (0.85) | BCL2 | |
| SCHEMBL19839483 | 0.93 | BCL2 (0.85) | BCL2 | |
| SCHEMBL29376973 | 0.91 | BCL2 (0.82) | BCL2 | |
| SCHEMBL20580518 | 0.91 | BCL2 (0.82) | BCL2 | |
| SCHEMBL19853624 | 0.86 | BCL2 (0.84) | BCL2 | |
| SCHEMBL20580667 | 0.86 | BCL2 (0.78) | BCL2 | |
| SCHEMBL29373371 | 0.86 | BCL2 (0.78) | BCL2 | |
| SCHEMBL29373716 | 0.85 | BCL2 (0.84) | BCL2 | |
| SCHEMBL19839927 | 0.85 | BCL2 (0.84) | BCL2 | |
| SCHEMBL20580464 | 0.85 | BCL2 (1.00) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672595-B1 | COMBINATION PRODUCT OF BCL-2 INHIBITOR AND CHEMOTHERAPEUTIC AGENT AND USE THEREOF IN THE PREVENTION AND/OR TREATMENT OF DISEASES | ASCENTAGE PHARMA SUZHOU CO LTD (CN) | 2021-07-21 | — | — | EP | disclosed |