Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23654825 | 0.95 | RAF1 (0.52) | RAF1BRAF | |
| SCHEMBL23654852 | 0.90 | RAF1 (0.49) | RAF1BRAF | |
| SCHEMBL23654349 | 0.83 | RAF1 (0.49) | RAF1BRAF | |
| SCHEMBL23654041 | 0.82 | RAF1 (0.53) | RAF1BRAF | |
| SCHEMBL23654359 | 0.81 | RAF1 (0.49) | RAF1BRAF | |
| SCHEMBL19016388 | 0.78 | RAF1 (0.52) | RAF1BRAF | |
| SCHEMBL23654848 | 0.78 | RAF1 (0.61) | RAF1BRAF | |
| SCHEMBL19015996 | 0.77 | BRAF (0.65) | RAF1BRAF | |
| SCHEMBL21250036 | 0.77 | RAF1 (0.46) | RAF1BRAF | |
| SCHEMBL21249948 | 0.73 | RAF1 (0.48) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390404-B1 | TRICYCLIC COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2021-07-21 | — | — | EP | disclosed |