Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008780 | 0.74 | RAF1 (0.45) | RAF1BRAF | |
| SCHEMBL20008343 | 0.71 | RAF1 (0.38) | RAF1BRAF | |
| SCHEMBL20008439 | 0.71 | RAF1 (0.67) | RAF1BRAF | |
| SCHEMBL19623269 | 0.70 | RAF1 (0.45) | RAF1BRAF | |
| SCHEMBL20009217 | 0.69 | RAF1 (0.39) | RAF1BRAF | |
| SCHEMBL22562030 | 0.68 | RAF1 (0.50) | RAF1BRAF | |
| SCHEMBL19328053 | 0.68 | RAF1 (0.55) | RAF1BRAF | |
| SCHEMBL19343154 | 0.67 | RAF1 (0.58) | RAF1BRAF | |
| SCHEMBL23654754 | 0.67 | RAF1 (0.62) | RAF1BRAF | |
| SCHEMBL22612768 | 0.66 | RAF1 (0.43) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390404-B1 | TRICYCLIC COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2021-07-21 | — | — | EP | disclosed |