Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAT | P04040 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ASPH | Q12797 | 2/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | AGER | Q15109 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23655027 | 1.00 | CAT (0.56) | CATKDM4EASPHKDM8ALDH1A1 | |
| SCHEMBL21012434 | 1.00 | CAT (0.56) | CATKDM4EASPHKDM8ALDH1A1 | |
| SCHEMBL21012542 | 1.00 | CAT (0.56) | CATKDM4EASPHKDM8ALDH1A1 | |
| SCHEMBL21012493 | 0.74 | CAT (0.63) | CATKDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL23655023 | 0.74 | CAT (0.63) | CATKDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL21012435 | 0.74 | CAT (0.63) | CATKDM4EALDH1A1MAPTALOX15 | |
| SCHEMBL21012433 | 0.74 | CAT (0.63) | CATKDM4EALDH1A1MAPTALOX15 | |
| Xeruborbactam SCHEMBL23655292 | 0.72 | CAT (1.00) | CAT | |
| Xeruborbactam SCHEMBL22854594 | 0.72 | CAT (1.00) | CAT | |
| Xeruborbactam SCHEMBL21012430 | 0.72 | CAT (1.00) | CAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3478693-B1 | BORONIC ACID DERIVATIVES AND THERAPEUTIC USES THEREOF | QPEX BIOPHARMA INC (US) | 2021-07-21 | — | — | EP | disclosed |