SCHEMBL23660320

SCHEMBL23660320

c1ccc(-c2ccc(N(c3ccc(-c4ccc5ccccc5c4)cc3)c3cccc(-c4cccc(-c5cccc6c5c5ccccc5n6-c5ccccc5)c4)c3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HSD17B1 P14061 1/20 0.32
HSD17B2 P37059 1/20 0.32
ALK Q9UM73 1/20 0.31
GSTP1 P09211 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
MET P08581 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24923368 1.00 KDM4E (0.35) KDM4EATML3MBTL1HSD17B1HSD17B2
SCHEMBL23659964 1.00 KDM4E (0.35) KDM4EATML3MBTL1HSD17B1HSD17B2
SCHEMBL23659894 1.00 KDM4E (0.35) KDM4EATML3MBTL1HSD17B1HSD17B2
SCHEMBL23659470 1.00 KDM4E (0.35) KDM4EATML3MBTL1HSD17B1HSD17B2
SCHEMBL25161344 1.00 KDM4E (0.35) KDM4EATML3MBTL1HSD17B1HSD17B2
SCHEMBL23660242 1.00 KDM4E (0.35) KDM4EATML3MBTL1HSD17B1HSD17B2
SCHEMBL23659498 1.00 KDM4E (0.35) KDM4EATML3MBTL1HSD17B1HSD17B2
SCHEMBL24679195 0.99 KDM4E (0.34) KDM4EATML3MBTL1HSD17B1HSD17B2
SCHEMBL24679189 0.99 KDM4E (0.35) KDM4EATML3MBTL1HSD17B1HSD17B2
SCHEMBL24678463 0.99 KDM4E (0.35) KDM4EATML3MBTL1HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021145429-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2021-07-22 WO disclosed