Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 8/20 | 0.59 |
| ▸ | WIZ | O95785 | 3/20 | 0.56 |
| ▸ | IKZF2 | Q9UKS7 | 9/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24289693 | 0.91 | CRBN (0.58) | CRBNWIZIKZF2 | |
| SCHEMBL29589983 | 0.91 | CRBN (0.58) | CRBNWIZIKZF2 | |
| SCHEMBL23267660 | 0.87 | CRBN (0.62) | CRBNWIZIKZF2 | |
| SCHEMBL22566723 | 0.86 | IKZF2 (0.65) | CRBNWIZIKZF2 | |
| SCHEMBL25988439 | 0.85 | CRBN (0.70) | CRBNWIZIKZF2 | |
| SCHEMBL22962697 | 0.85 | CRBN (0.66) | CRBNWIZIKZF2 | |
| SCHEMBL24319331 | 0.85 | CRBN (0.69) | CRBNWIZIKZF2 | |
| SCHEMBL17552859 | 0.85 | CRBN (0.69) | CRBNWIZIKZF2 | |
| SCHEMBL34465960 | 0.84 | CRBN (0.65) | CRBNWIZIKZF2 | |
| SCHEMBL34466761 | 0.84 | CRBN (0.65) | CRBNWIZIKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210221802-A1 | NOVEL CHROMAN DERIVATIVES HAVING ESTROGEN RECEPTOR DEGRADATION ACTIVITY AND USES THEREOF | ACCUTAR BIOTECHNOLOGY INC. (US) | 2021-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210221802-A1 | NOVEL CHROMAN DERIVATIVES HAVING ESTROGEN RECEPTOR DEGRADATION ACTIVITY AND USES THEREOF | ESR2, ESR1, ESRRG | CRBN 324/4885WIZ 4786/4885IKZF2 3471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.