⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27386849 | 0.84 | — | — | |
| SCHEMBL7321 | 0.82 | — | — | |
| SCHEMBL11841381 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL3855161 | 0.80 | CA12 (0.38) | — | |
| Hydrochloric Acid SCHEMBL5012159 | 0.80 | — | — | |
| SCHEMBL13434243 | 0.80 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL16607618 | 0.80 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL27693198 | 0.78 | CA12 (0.36) | — | |
| SCHEMBL25224342 | 0.76 | TSHR (0.43) | — | |
| SCHEMBL4874102 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3176163-B1 | NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | IAC IN NAT UNIV CHUNGNAM (KR) | 2019-04-17 | — | — | EP | claimed |
| US-20170152268-A1 | NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | MOTHER'S PHARMACEUTICAL CO., LTD. (KR) | 2017-06-01 | — | — | US | claimed |
| WO-2024101402-A1 | PHARMACEUTICAL COMPOSITION CONTAINING CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT AGAINST HRAS AND NRAS | 中外製薬株式会社 | 2024-05-16 | — | — | WO | disclosed |
| US-20240158446-A1 | CYCLIC COMPOUND HAVING SELECTIVE INHIBITORY ACTION ON KRAS OVER HRAS AND NRAS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-05-16 | — | — | US | disclosed |
| WO-2024101386-A1 | CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS | 中外製薬株式会社 | 2024-05-16 | — | — | WO | disclosed |
| WO-2024096023-A1 | METHOD FOR REMOVING DIBENZOFULVENE OR DIBENZOFULVENE DERIVATIVE | 中外製薬株式会社 | 2024-05-10 | — | — | WO | disclosed |
| US-20240148821-A1 | PHARMACEUTICAL USE OF CYCLIC PEPTIDE COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-05-09 | — | — | US | disclosed |
| WO-2024085235-A1 | METHOD FOR PRODUCING CYCLIC PEPTIDE CRYSTALS | 中外製薬株式会社 | 2024-04-25 | — | — | WO | disclosed |
| WO-2024080308-A1 | COMPOSITION CONTAINING PEPTIDE, SURFACTANT, AND POLYMER | 中外製薬株式会社 | 2024-04-18 | — | — | WO | disclosed |
| US-20240124517-A1 | METHOD FOR PRODUCING PEPTIDE COMPOUND CONTAINING N-SUBSTITUTED-AMINO ACID RESIDUE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-04-18 | — | — | US | disclosed |
| WO-2024080333-A1 | METHOD FOR PRODUCING N-SUBSTITUTED AMINO ACID RESIDUE-CONTAINING CYCLIC PEPTIDE COMPOUND | 中外製薬株式会社 | 2024-04-18 | — | — | WO | disclosed |
| CN-100462351-C | Amino acids having affinity for the alpha 2 delta protein | WARNER LAMBERT CO (US) | 2009-02-18 | — | — | CN | disclosed |
| US-20070244145-A1 | Cyclic Amine Compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2007-10-18 | — | — | US | disclosed |
| EP-1757605-A1 | CYCLIC AMINE COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2007-02-28 | — | — | EP | disclosed |
| CN-1817854-A | Amino acids with affinity for the alpha-2-delta protein | WARNER LAMBERT CO (US) | 2006-08-16 | — | — | CN | disclosed |
| CN-1768051-A | Substituted pyrazoles | MERCK PATENT GMBH (DE) | 2006-05-03 | — | — | CN | disclosed |
| CN-1674884-A | Synergistic combination of an alpha-2-delta ligand and a PDEV inhibitor for use in the treatment of pain | PFIZER LTD (US) | 2005-09-28 | — | — | CN | disclosed |
| CN-1653036-A | Amino acids having affinity for the alpha 2 delta protein | WARNER LAMBERT CO (US) | 2005-08-10 | — | — | CN | disclosed |
| CN-1060161-C | N-substituted phenylcarbamic acid derivatives, process for production thereof, agricultural and horticultural fungicides, intermediates of derlvatives and process for production thereof | NIHON NOHYAKU CO LTD (JP) | 2001-01-03 | — | — | CN | disclosed |
| CN-1132744-A | N-substituted phenylcarbamic acid derivatives, process for production thereof, agricultural and horticultural fungicides, intermediates of derlvatives and process for production thereof | NIHON NOHYAKU CO LTD (JP) | 1996-10-09 | — | — | CN | disclosed |