Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 13/20 | 0.49 |
| ▸ | RAB9A | P51151 | 12/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23387558 | 0.98 | NPC1 (0.47) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL22007067 | 0.98 | NPC1 (0.47) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL23667718 | 0.94 | NPC1 (0.44) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL22007073 | 0.94 | NPC1 (0.53) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL22007066 | 0.94 | NPC1 (0.53) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL22007083 | 0.94 | NPC1 (0.53) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL22686511 | 0.94 | NPC1 (0.49) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL23667801 | 0.92 | NPC1 (0.53) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL22686048 | 0.91 | NPC1 (0.53) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL23667941 | 0.90 | KDM4E (0.55) | NPC1RAB9AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210226132-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2021-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210226132-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | SLC39A14, SLC39A7, SLC39A3 | NPC1 1687/4885RAB9A 3447/4885KDM4E 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.