SCHEMBL23668366

SCHEMBL23668366

Oc1ccc2cccc3c2c1C=CC3

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.41
TSHR P16473 2/20 0.41
CDK2 P24941 1/20 0.37
ALDH1A1 P00352 5/20 0.34
HSD17B10 Q99714 3/20 0.34
HPGD P15428 3/20 0.34
CYP1A2 P05177 2/20 0.34
CYP1A1 P04798 1/20 0.34
CYP1B1 Q16678 1/20 0.34
KDM4E B2RXH2 3/20 0.33
TYMS P04818 1/20 0.33
CYP2C19 P33261 1/20 0.33
LMNA P02545 1/20 0.32
CTDSP1 Q9GZU7 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
PTPN22 Q9Y2R2 1/20 0.31
DNMT1 P26358 1/20 0.31
CACNA1B Q00975 1/20 0.31
APBA1 Q02410 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propane SCHEMBL27851333 0.94 CYP3A4 (0.36) CYP3A4TSHRCDK2ALDH1A1HSD17B10
SCHEMBL2881023 0.92 CYP3A4 (0.35) CYP3A4TSHRCDK2CYP2C19
SCHEMBL27471410 0.91 CDK2 (0.35) CYP3A4TSHRCDK2ALDH1A1HSD17B10
Fluorene SCHEMBL27673944 0.89 TSHR (0.41) CYP3A4TSHRCDK2ALDH1A1HSD17B10
SCHEMBL10542837 0.81 TSHR (0.43) CYP3A4TSHRALDH1A1HSD17B10HPGD
SCHEMBL3700917 0.79 CYP3A4 (0.41) CYP3A4TSHRALDH1A1HSD17B10HPGD
SCHEMBL25429169 0.79 TSHR (0.41) CYP3A4TSHRALDH1A1HSD17B10HPGD
SCHEMBL20377849 0.79 CYP3A4 (0.41) CYP3A4TSHRALDH1A1HSD17B10HPGD
SCHEMBL28418222 0.79 CYP3A4 (0.41) CYP3A4TSHRALDH1A1HSD17B10HPGD
SCHEMBL23546524 0.79 CYP3A4 (0.41) CYP3A4TSHRALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1066760-A FUNGICIDAL FORMULATIONS SCHERING AGROCHEMICALS LTD (GB) 1992-12-09 CN claimed
CN-110035739-B Dye composition comprising 12-hydroxystearic acid, an organic amine and a dye 欧莱雅 2022-05-10 CN disclosed
CN-113861382-A Crystalline epoxy resin, epoxy resin composition, and cured epoxy resin 日铁化学材料株式会社 2021-12-31 CN disclosed
US-20210229047-A1 DOPED MEMBRANES GAMBRO LUNDIA AB (SE) 2021-07-29 US disclosed
CN-102070770-B Phosphorous epoxy resin curing agent and preparation method thereof UNIV SHENYANG CHEMICAL TECH 2012-11-28 CN disclosed
CN-102070770-A Phosphorous epoxy resin curing agent and preparation method thereof UNIV SHENYANG CHEMICAL TECH 2011-05-25 CN disclosed
CN-1054024-C Fungicidal formulations SCHERING AGROCHEMICALS LTD (GB) 2000-07-05 CN disclosed
CN-1066760-A FUNGICIDAL FORMULATIONS SCHERING AGROCHEMICALS LTD (GB) 1992-12-09 CN disclosed
CN-1066760-A FUNGICIDAL FORMULATIONS SCHERING AGROCHEMICALS LTD (GB) 1992-12-09 CN disclosed