Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 17/20 | 0.88 |
| ▸ | BTK | Q06187 | 17/20 | 0.88 |
| ▸ | EGFR | P00533 | 3/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23673750 | 1.00 | JAK3 (0.88) | JAK3BTKEGFR | |
| SCHEMBL22496849 | 0.93 | JAK3 (1.00) | JAK3BTKEGFR | |
| SCHEMBL22496854 | 0.93 | JAK3 (1.00) | JAK3BTKEGFR | |
| SCHEMBL14801750 | 0.92 | EGFR (1.00) | JAK3BTKEGFR | |
| SCHEMBL14801705 | 0.92 | EGFR (1.00) | JAK3BTKEGFR | |
| SCHEMBL14821931 | 0.92 | EGFR (1.00) | JAK3BTKEGFR | |
| SCHEMBL23690741 | 0.91 | JAK3 (0.90) | JAK3BTKEGFR | |
| SCHEMBL23690756 | 0.91 | JAK3 (0.90) | JAK3BTKEGFR | |
| SCHEMBL23690742 | 0.91 | JAK3 (0.90) | JAK3BTKEGFR | |
| SCHEMBL14801510 | 0.88 | EGFR (0.87) | JAK3BTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244055-A | Pyrimido five-membered ring derivative and application thereof | 江苏先声药业有限公司 | 2022-10-25 | — | — | CN | disclosed |
| WO-2021147953-A1 | PYRIMIDO FIVE-MEMBERED RING DERIVATIVE AND APPLICATION THEREOF | 江苏先声药业有限公司 | 2021-07-29 | — | — | WO | disclosed |
| WO-2021147953-A1 | PYRIMIDO FIVE-MEMBERED RING DERIVATIVE AND APPLICATION THEREOF | 江苏先声药业有限公司 | 2021-07-29 | — | — | WO | disclosed |