Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.68 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NT5E | P21589 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15158230 | 1.00 | ADORA2A (0.70) | ADORA2AADORA3ADORA2BADORA1ADRA1A | |
| SCHEMBL271324 | 1.00 | ADORA2A (0.70) | ADORA2AADORA3ADORA2BADORA1ADRA1A | |
| SCHEMBL15158228 | 0.92 | ADORA2A (0.72) | ADORA2AADORA3ADORA2BADORA1ADRA1A | |
| SCHEMBL4539668 | 0.92 | ADORA2A (0.72) | ADORA2AADORA3ADORA2BADORA1ADRA1A | |
| SCHEMBL271016 | 0.92 | ADORA2A (0.72) | ADORA2AADORA3ADORA2BADORA1ADRA1A | |
| Water SCHEMBL489161 | 0.91 | ADORA2A (0.71) | ADORA2AADORA3ADORA2BADORA1ADRA1A | |
| SCHEMBL1985230 | 0.90 | ADORA2A (0.64) | ADORA2AADORA3ADORA2BADORA1ADRA1A | |
| SCHEMBL272093 | 0.89 | ADORA2A (0.69) | ADORA2AADORA3ADORA2BADORA1ADRA1A | |
| SCHEMBL2883494 | 0.86 | ADORA2A (0.65) | ADORA2AADORA3ADORA2BADORA1ADRA1A | |
| SCHEMBL18556282 | 0.84 | ADORA2A (0.80) | ADORA2AADORA3ADORA2BADORA1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2366396-A1 | Myocardial perfusion imaging using adenosine receptor agonists | Gilead Palo Alto, Inc. (US) | 2011-09-21 | — | — | EP | disclosed |