⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL123825 | 0.77 | — | — | |
| SCHEMBL596658 | 0.74 | — | — | |
| SCHEMBL15382459 | 0.72 | — | — | |
| SCHEMBL1509705 | 0.72 | — | — | |
| SCHEMBL6566971 | 0.72 | — | — | |
| SCHEMBL20011557 | 0.72 | — | — | |
| SCHEMBL6842689 | 0.72 | — | — | |
| SCHEMBL19891916 | 0.72 | — | — | |
| SCHEMBL94433 | 0.72 | — | — | |
| SCHEMBL11189303 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021151004-A1 | COMPOSITIONS AND METHODS FOR INCREASING OR ENHANCING TRANSDUCTION OF GENE THERAPY VECTORS AND FOR REMOVING OR REDUCING IMMUNOGLOBULINS | SPARK THERAPEUTICS, INC. (US) | 2021-07-29 | — | — | WO | disclosed |