Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 13/20 | 0.65 |
| ▸ | P2RX1 | P51575 | 7/20 | 0.65 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.65 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | IKBKB | O14920 | 1/20 | 0.56 |
| ▸ | CHUK | O15111 | 1/20 | 0.56 |
| ▸ | FLT3 | P36888 | 1/20 | 0.56 |
| ▸ | MYLK | Q15746 | 1/20 | 0.56 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30100476 | 1.00 | TMPRSS4 (0.65) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL30100514 | 0.92 | TMPRSS4 (0.64) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL23675454 | 0.92 | TMPRSS4 (0.64) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL26096971 | 0.90 | P2RX1 (0.59) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL23675416 | 0.90 | TMPRSS4 (0.59) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL23675407 | 0.89 | TMPRSS4 (0.61) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL30100480 | 0.89 | TMPRSS4 (0.61) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL23675418 | 0.89 | P2RX1 (0.62) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL26096505 | 0.88 | TMPRSS4 (0.57) | TMPRSS4P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL26099973 | 0.88 | MEN1 (0.54) | TMPRSS4P2RX1P2RX4P2RX7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230140290-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | THE BOARD OF REGENTS OF THE UNIV OF TEXAS SY (US) | 2023-05-04 | — | — | US | disclosed |
| WO-2021151104-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230140290-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | EIF2AK2, SARS1, ACE | TMPRSS4 526/4885P2RX1 3088/4885P2RX4 2856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.