Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.62 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.62 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.62 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.55 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.55 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | RHOA | P61586 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1259529 | 0.86 | GUCY1B2 (0.59) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL15197892 | 0.84 | CYP1A2 (0.58) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL1259501 | 0.81 | CYP1A2 (0.55) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL1770090 | 0.81 | SMN1; SMN2 (0.56) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL31399941 | 0.81 | CYP1A2 (0.55) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL10928797 | 0.81 | CYP1A2 (0.55) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL19144359 | 0.81 | TDP1 (0.56) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL16309117 | 0.79 | SMN1; SMN2 (0.54) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1CYP1A2 | |
| SCHEMBL17598037 | 0.77 | GUCY1B2 (1.00) | GUCY1B2GUCY1A2GUCY1A1GUCY1B1ALDH1A1 | |
| 4-Nitrocatechol SCHEMBL156909 | 0.77 | TSHR (0.69) | CYP1A2ALDH1A1GPR35TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2368885-A1 | Derivatives of phenazine useful to treat cancer | Université de la Méditerranée (Aix-Marseille II) (FR) | 2011-09-28 | — | — | EP | claimed |
| WO-2011117830-A1 | DERIVATIVES OF PHENAZINE USEFUL TO TREAT CANCER | Université de la Méditerranée AIX-Marseille II (FR) | 2011-09-29 | — | — | WO | disclosed |
| EP-2368885-A1 | Derivatives of phenazine useful to treat cancer | Université de la Méditerranée (Aix-Marseille II) (FR) | 2011-09-28 | — | — | EP | disclosed |
| EP-2368885-A1 | Derivatives of phenazine useful to treat cancer | Université de la Méditerranée (Aix-Marseille II) (FR) | 2011-09-28 | — | — | EP | disclosed |