Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23677171 | 0.86 | SCN9A (0.58) | SCN9ASCN5A | |
| SCHEMBL18570783 | 0.81 | SCN9A (0.48) | SCN9ASCN5A | |
| SCHEMBL23677142 | 0.69 | SCN9A (0.66) | SCN9ASCN5A | |
| SCHEMBL18571061 | 0.69 | SCN9A (0.54) | SCN9ASCN5A | |
| SCHEMBL18571131 | 0.69 | SCN9A (0.53) | SCN9ASCN5A | |
| SCHEMBL20697687 | 0.68 | SCN9A (0.44) | SCN9ASCN5A | |
| SCHEMBL19429998 | 0.68 | SCN9A (0.72) | SCN9ASCN5A | |
| SCHEMBL21075337 | 0.68 | SCN9A (0.47) | SCN9ASCN5A | |
| SCHEMBL22912721 | 0.68 | SCN9A (0.55) | SCN9ASCN5A | |
| SCHEMBL24263958 | 0.67 | SCN9A (0.48) | SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854782-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | Genentech, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |