Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15612878 | 0.81 | HTR2B (0.60) | MEN1KMT2AMAPTADORA3SLC6A3 | |
| SCHEMBL15612959 | 0.80 | HTR2B (0.62) | MEN1KMT2AMAPTADORA3SLC6A3 | |
| SCHEMBL17115693 | 0.80 | MEN1 (0.56) | MEN1KMT2AMAPTADORA3SLC6A3 | |
| SCHEMBL15612856 | 0.80 | HTR2B (0.62) | MEN1KMT2AMAPTADORA3SLC6A3 | |
| SCHEMBL15612976 | 0.79 | MEN1 (0.61) | MEN1KMT2AMAPTADORA3SLC6A3 | |
| SCHEMBL15613130 | 0.79 | HTR2B (0.78) | MEN1KMT2AMAPTADORA3SLC6A3 | |
| SCHEMBL15613017 | 0.78 | MEN1 (0.53) | MEN1KMT2AMAPTADORA3SLC6A3 | |
| SCHEMBL15573630 | 0.76 | MEN1 (0.69) | MEN1KMT2AMAPTADORA3SLC6A3 | |
| SCHEMBL15575769 | 0.76 | MEN1 (0.69) | MEN1KMT2AMAPTSMN1; SMN2SIRT2 | |
| SCHEMBL15613023 | 0.76 | MEN1 (0.69) | MEN1KMT2AMAPTSMN1; SMN2SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2890375-B1 | SULFAMOYL-ARYLAMIDES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-07-28 | — | — | EP | disclosed |