Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.76 |
| ▸ | TP53 | P04637 | 14/20 | 0.64 |
| ▸ | LMNA | P02545 | 12/20 | 0.64 |
| ▸ | MAPT | P10636 | 11/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17115717 | 0.99 | HTR2B (0.77) | HTR2BTP53LMNAMAPTALDH1A1 | |
| SCHEMBL15612908 | 0.91 | HTR2B (0.75) | HTR2BTP53LMNAMAPTALDH1A1 | |
| SCHEMBL15613147 | 0.91 | TP53 (0.71) | HTR2BTP53LMNAMAPTALDH1A1 | |
| SCHEMBL15613065 | 0.89 | MAPT (0.71) | HTR2BTP53LMNAMAPTALDH1A1 | |
| SCHEMBL17094994 | 0.89 | HTR2B (0.70) | HTR2BTP53LMNAMAPTALDH1A1 | |
| SCHEMBL17095026 | 0.89 | HTR2B (0.70) | HTR2BTP53LMNAMAPTALDH1A1 | |
| SCHEMBL15076790 | 0.89 | HTR2B (0.70) | HTR2BTP53LMNAMAPTALDH1A1 | |
| SCHEMBL17094983 | 0.89 | HTR2B (0.70) | HTR2BTP53LMNAMAPTALDH1A1 | |
| SCHEMBL15613008 | 0.89 | HTR2B (0.72) | HTR2BTP53LMNAMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL15573591 | 0.88 | HTR2B (0.68) | HTR2BTP53LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2890375-B1 | SULFAMOYL-ARYLAMIDES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-07-28 | — | — | EP | disclosed |