Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13863120 | 0.93 | TDP1 (0.44) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL26282496 | 0.93 | TDP1 (0.44) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL17123278 | 0.93 | TDP1 (0.44) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL13488578 | 0.93 | TDP1 (0.44) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL15404813 | 0.90 | TDP1 (0.46) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL26282526 | 0.89 | TDP1 (0.41) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL28054471 | 0.88 | TSHR (0.44) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL26282531 | 0.88 | TDP1 (0.40) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL19718601 | 0.86 | POLB (0.39) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL10629482 | 0.85 | TDP1 (0.49) | TDP1POLBAPEX1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288496-B2 | Contact lens and its manufacturing method | NIPPON CONTACT LENS INC. (JP) | 2012-10-16 | — | — | US | disclosed |
| US-20110237701-A1 | CONTACT LENS AND ITS MANUFACTURING METHOD | NIPPON CONTACT LENS INC. (JP) | 2011-09-29 | — | — | US | disclosed |
| EP-2369370-A2 | Contact lens and its manufacturing method | Nippon Contact Lens Inc. (JP) | 2011-09-28 | — | — | EP | disclosed |