Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23678380 | 0.90 | KCNH2 (0.39) | KCNH2CACNA1BCYP17A1CYP2C9CYP2C19 | |
| SCHEMBL23678491 | 0.83 | KCNH2 (0.38) | KCNH2CACNA1BKDM4EALDH1A1LMNA | |
| SCHEMBL23678412 | 0.81 | KCNH2 (0.39) | KCNH2CACNA1BMAOBCYP2D6 | |
| SCHEMBL23678346 | 0.77 | KCNH2 (0.39) | KCNH2CACNA1BKDM4EALDH1A1LMNA | |
| SCHEMBL18896125 | 0.76 | KDM4E (0.56) | KCNH2CACNA1BCYP2C9CYP2C19KDM4E | |
| SCHEMBL23678396 | 0.73 | CACNA1B (0.41) | KCNH2CACNA1BKDM4EALDH1A1LMNA | |
| SCHEMBL21834242 | 0.71 | MAOB (0.39) | KCNH2CACNA1BCYP17A1CYP2C9CYP2C19 | |
| SCHEMBL23678495 | 0.69 | MAOB (0.38) | KCNH2CACNA1BCYP2C9MAOB | |
| SCHEMBL23678388 | 0.69 | MAOB (0.38) | KCNH2CACNA1BCYP2C9MAOB | |
| SCHEMBL23678359 | 0.69 | MAOB (0.38) | KCNH2CACNA1BCYP2C9MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854788-A1 | COMPOUND CONTAINING OXADIAZOLE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | SK Biopharmaceuticals Co., Ltd. (KR) | 2021-07-28 | — | — | EP | disclosed |